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Drug Solubility in Water

 Descriptive Terms
   Very Soluble
   Freely Soluble
   Soluble
   Sparingly Soluble
   Slightly Soluble
   Very Slightly Soluble
   Practically Insoluble
 Parts of Solvent/1 Part of Solute
   Less than 1
   From 1 to 10
   From 10 to 30
   From 30 to 100
   From 100 to 1,000
   From 1,000 to 10,000
   10,000 and Over
 Solubility Range
  >1,000        mg/mL  (>100%)
   100~1,000 mg/mL  (10~100%)
     33~100     mg/mL  (3.3~10%)
     10~33       mg/mL  (1~3.3%)
       1~10       mg/mL  (0.1~1%)
       0.1~1      mg/mL  (0.01~0.1%)
     <0.1          mg/mL  (<0.01%)

Injectable Long-Acting Formulations Approved by the FDA

   

Peptides

 

Proteins